ASH News Daily - Monday, December 12, 2011 - (Page B-8)

Page B–8 ® ASH NewS DAily Michael Dengler Payal Desai Anagha Deshpande Anamika Dhyani Marina Díaz-Beyá Jana Diestelhorst Jan Dörr Guilherme dos Santos Bhavya Doshi Hong-Yan Du Jarrod Dudakov Michael Eckrich Homare Eda Anna Eiring Judith Eisenbacher Abdelouahid ElKhattouti Inas El-Najjar Kolja Eppert Erica Esrick Mark Ewalt Chao Fang Shatha Farhan Matthew Farren Jessie-Farah Fecteau Carlos Fernández de Larrea Regiane Ferreira Mareike Florek Bree Foley Courtney Follit Caroline Fong Benjamin Frisch Verena Gaidzik Sheley Gambero Chintan Gandhi Saravanan Ganesan Chunyan Gao Hong (Jenny) Gao Daniel Garcia Santos Karine Gauthier Charles Gawad Xueling Ge Yipeng Geng Barbara Ghinassi Arnab Ghosh Silvia Giannini Saar Gill Hamilton GimenesTeixeira Ruchika Goel Caryn Gonsalves Hideki Goto Jennifer Goy Susumu Goyama Cliona Grant Sandra Grass Adam Greenbaum Sarah Greenblatt Michael Greene Patrick Griffin Lana Grkovic Vera Grossmann Renata Grozovsky Xiwen Gu Devi Gunasekera Li Guo Kelley Haarberg Eunsil Hahm Alan Hanash Benjamin Hanfstein Patrick Hanley Jason Harb Michael Harr Steffen Hartrampf Sidonie HartridgeLambert Kimberly Hartwell Ryo Hatano Catriona Hayes Shan He Yongzheng He Anna Hecht Ricardo Helman Marieka Helou Sarah Herman Takafumi Hiramoto Lucy Hodge Amber Hogart Pleun Hombrink Noah Hornick Marie-Anne Hospital Hsin-An Hou Brett Houston Xiaomeng Huang Michael Hudecek Krystalyn Hudson Malin Hultcrantz Hyacinth Hyacinth Ilaria Iacobucci Yoshihiro Inamoto Andrew Innes Chisako Iriyama Jun Ishihara Yuichi Ishikawa Takeshi Isoda Monday, December 12, 2011 Ghayas Issa Lacramioara Ivanciu Chika Iwamoto Pekka Jaako Rachael Jackman Ryan Jacobs Michael Jaglal Salvia Jain Anna Jankowska Reema Jasuja Mira Jeong Andres Jerez Shundong Ji Cui Jian Moonjung Jung Stephan Kadauke Allison Kaeding Alissa Kahn Demetrios Kalaitzidis Kenjiro Kamezaki Ashley Kamimae-Lanning Chihiro Kaminaga Shibichakravarthy Kannan Rick Kapur Julia Kase Hiroo Katsuya Christiane Katzerke Ganesan Keerthivasan Marc Kerenyi Aasma Khan Irum Khan »» ABSTRACT AWARDS Page B-22 Abstract Awards «« From Page B-4 Alice Cheung Rufaro Chitsike Sharon Choi HyoJung Choo Marie-Lorraine Chretien S. Haihua Chu Curtis Clark E. Leila Clay Thomas Clozel Marina Colella Jeffrey Cooney Michael Copley Mirko Corselli Benedetta Costantini Caitlin Costello Rita Coutinho Kimberly Cramer Elizabeth Csaszar Elena Cubedo Renato Cunha Ann Dahlberg Ali Danesh Catherine Daniel Nadia Danilova Rebecca Davis-Harrison Mark Dawson Lucia de Siqueira Michael Delaney Changwang Deng Now Recruiting... A New Clinical Trial for Patients With Multicentric Castleman’s Disease About Multicentric Castleman’s Disease (MCD) MCD is a rare disorder characterized by abnormal noncancerous growths in the lymphatic tissues at multiple sites throughout the body and by systemic manifestations such as fever, night sweats, fatigue, anorexia, and wasting. Also known as giant lymph node hyperplasia or angiofollicular lymph node hyperplasia, MCD can also be misdiagnosed as malignant lymphoma. There is no currently approved treatment for MCD. Study Design 78 Total patients (2:1) Study Overview Ortho Biotech Oncology Research and Development, a unit of Centocor Research and Development, Inc., is conducting a pivotal registration study on MCD. Receive investigational treatment + BSC every 3 weeks Receive placebo + BSC every 3 weeks Primary Objective The primary objective of this study is to demonstrate that an investigational medicine plus best supportive care (BSC) is better than placebo plus BSC in patients with symptomatic MCD. About the Investigational Medicine The investigational medicine is a chimeric monoclonal antibody that blocks the function of the cytokine IL-6. Patients who do not respond to placebo + BSC may be switched to the investigational treatment + BSC The Castleman’s Study www.CastlemansResearch.com CNTO-MCD-ENG14 10 Nov 2009 The Castleman’s Study is being conducted in approximately 24 countries worldwide. As this trial presents a unique opportunity for patients with MCD, you may wish to consider referring your patients with this condition. To find out more, please visit www.CastlemansResearch.com 

Table of Contents for the Digital Edition of ASH News Daily - Monday, December 12, 2011

ASH News Daily - Monday, December 12, 2011

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