ASH News Daily - Tuesday, December 13, 2011 - (Page A-1)

Celebrating 10 Years ASH NEWS DAILY 53rd Annual Meeting of the American Society of Hematology ® Issue 4, Section A Tuesday, December 13, 2011 San Diego, CA Read this issue online at www.nxtbook.com/nxtbooks/ashnewsdaily2011_Tuesday/ Schedule 7:30 – 9:00 a.m. Simultaneous Sessions 7:30 – 9:00 a.m. Late-Breaking Abstracts Session San Diego Convention Center Hall AB 7:30 – 9:00 a.m. Special Symposium on the Basic Science of Hemostasis and Thrombosis (invited presentations) San Diego Convention Center Ballroom 20D 9:30 – 9:45 a.m. Announcement of the Dameshek Prize and the Stratton Medal San Diego Convention Center Hall AB 9:45 – 11:15 a.m. Presidential Symposium San Diego Convention Center Hall AB 11:15 – 11:30 a.m. Business Meeting San Diego Convention Center Hall AB 12:00 noon – 1:00 p.m. Best of ASH San Diego Convention Center Room 20ABC 12:00 noon – 1:00 p.m. Special Symposium on the Basic Science of Hemostasis and Thrombosis (simultaneous oral sessions) San Diego Convention Center Rooms 24, 25, 29, 30, 31, 33 IN THIS SECTION Plausability of Platelets in Immunity A-2 Neutrophils and TRALI A-3 Bone Marrow Failure: Success May Be on the Horizon A-6 Patient Communication: It Matters to Them – And You A-7 D r. E. Donnall Thomas, a Nobel Prize laureate, is honored on an annual basis at the ASH annual meeting in the form of a Monday morning lecture. The E. Donnall Thomas Lecture and Prize recognizes pioneering research achievements in hematology that have represented a paradigm shift or significant discovery in the field. This year’s winner, Dr. George Q. Daley, is world renowned for his work in stem cell research, and yesterday he delivered a wonderful lecture titled “Hematopoietic, Embryonic, and Induced Pluripotent Stem Cells: Diseases, Myths, and Medicines.” The lecture focused on the promises and challenges of applying stem cells, specifically embryonic stem cells, to the study and treatment of disease. During the lecture, Dr. Daley shared how his early research on chronic myeloid leukemia (CML) and BCR-ABL led to work on hematopoietic stem cells and subsequently to genetically modified human BREAKING NEWS It’s Not Too Late to Make a Break By JoSeph Mikhael, Md, Med T AB of the San Diego Convention Center. The Late-Breaking Abstract session, a relatively new addition to the annual meeting, is not to be missed on the final day. This session showcases six abstracts whose results were only available six weeks ago and will be sure to capture the attention of many, as genuinely ground-breaking data, in both clinical and basic science fields, will be presented. A Norwegian randomized, con- for Late-Breaking Abstracts trolled trial of catheter-directed thombolysis (CDT) in proximal deep-vein thrombosis (The CaVenT study) will be presented by Dr. Tone Rønnaug Enden, Oslo University Hospital. Post thrombotic syndrome (PTS) remains a serious long-term complication of many patients who experience a DVT. Rapid patency of the vessel theoretically would reduce the incidence and severity of PTS, but very little has been done to validate this prospectively. This study was designed to reduce PTS by adding CDT to standard anticoagulation. With more than 200 patients with acute iliofemoral DVT enrolled, his just in … late-breaking abstracts are about to be presented at 7:30 a.m. in Hall there was a significant reduction in PTS in patients who received CDT. This, however, comes at the cost of increased bleeding, including major bleeding episodes. Come find out more about who may best benefit from this procedure. Lymphoma biology will also be highlighted in the session. Dr. Aurelien Marabelle, Stanford University, will present fascinating data on the role of regulatory T cells (Tregs) and how they may be manipulated to enhance tumor response, even at distant sites such as CNS lymphoma. This unique »» ABSTRACTS Page A-7 A Beautiful Memory of a Career Committed to Science By Michael R. BiShop, Md Dr. George Q. Daley listens to his introduction as he prepares to present the E. Donnall Thomas Lecture, “Hematopoietic, Embryonic, and Induced Pluripotent Stem Cells: Diseases, Myths, and Medicine.” embryonic stem cells. Dr. Daley, who has long been a steady voice of reason regarding embryonic stem cell research, highlighted the overzealous and unrealistic hype in the earliest days of embryonic stem cell research, succinctly took the audi- ence through past research, and brought us up to date on the most recent advances in this field, including his own work on genetically modified human embryonic »» E. DONNALL THOMAS Page A-7 https://www.nxtbook.com/nxtbooks/ashnewsdaily2011_Tuesday/

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ASH News Daily - Tuesday, December 13, 2011

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